Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae.
Identifieur interne : 000E26 ( Main/Exploration ); précédent : 000E25; suivant : 000E27Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae.
Auteurs : Muhammad Abdul Mojid Mondol [Allemagne] ; Musrat Zahan Surovy [Bangladesh] ; M Tofazzal Islam [Bangladesh] ; Anja Schüffler [Allemagne] ; Hartmut Laatsch [Allemagne]Source :
- Journal of agricultural and food chemistry [ 1520-5118 ] ; 2015.
Descripteurs français
- KwdFr :
- Extraits de plantes (composition chimique), Extraits de plantes (isolement et purification), Extraits de plantes (pharmacologie), Hypocreales (composition chimique), Légumes (composition chimique), Phytophthora (cytologie), Phytophthora (effets des médicaments et des substances chimiques), Spores (cytologie), Spores (effets des médicaments et des substances chimiques), Structure moléculaire (MeSH), Trichothécènes (composition chimique), Trichothécènes (isolement et purification), Trichothécènes (pharmacologie).
- MESH :
- composition chimique : Extraits de plantes, Hypocreales, Légumes, Trichothécènes.
- cytologie : Phytophthora, Spores.
- effets des médicaments et des substances chimiques : Phytophthora, Spores.
- isolement et purification : Extraits de plantes, Trichothécènes.
- pharmacologie : Extraits de plantes, Trichothécènes.
- Structure moléculaire.
English descriptors
- KwdEn :
- Hypocreales (chemistry), Molecular Structure (MeSH), Phytophthora (cytology), Phytophthora (drug effects), Plant Extracts (chemistry), Plant Extracts (isolation & purification), Plant Extracts (pharmacology), Spores (cytology), Spores (drug effects), Trichothecenes (chemistry), Trichothecenes (isolation & purification), Trichothecenes (pharmacology), Vegetables (chemistry).
- MESH :
- chemical , chemistry : Plant Extracts, Trichothecenes.
- chemistry : Hypocreales, Vegetables.
- cytology : Phytophthora, Spores.
- drug effects : Phytophthora, Spores.
- chemical , isolation & purification : Plant Extracts, Trichothecenes.
- chemical , pharmacology : Plant Extracts, Trichothecenes.
- Molecular Structure.
Abstract
The cytotoxicity of the extract obtained from Myrothecium roridum M10 and a characteristic (1)H signal at δH ∼8 led to the assumption that verrucarin/roridin-type compounds were present. Upscaling on rice medium led to the isolation of four new metabolites: verrucarins Y (1) and Z (6) (macrocyclic trichothecenes), bilain D (12) (a diketopiperazine derivative), and hamavellone C (14) (an unusual cyclopropyl diketone). In addition, nine known trichothecenes [verrucarin A (3), 16-hydroxyverrucarin A (5), verrucarin B (7), 16-hydroxyverrucarin B (8), verrucarin J (2), verrucarin X (4), roridin A (9), roridin L-2 (10), and trichoverritone (11)] and a bicyclic lactone [myrotheciumone A (15)] were identified. Their structures and configurations were determined by spectroscopic methods, published data, Mosher's method, and considering biosyntheses. Some trichothecenes showed motility inhibition followed by lysis of the zoospores against devastating Phytophthora nicotianae within 5 min. Compounds 2, 3, 7, and 9 also exhibited potent activities against Candida albicans and Mucor miehei.
DOI: 10.1021/acs.jafc.5b02366
PubMed: 26320597
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae.</title><author><name sortKey="Mondol, Muhammad Abdul Mojid" sort="Mondol, Muhammad Abdul Mojid" uniqKey="Mondol M" first="Muhammad Abdul Mojid" last="Mondol">Muhammad Abdul Mojid Mondol</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Surovy, Musrat Zahan" sort="Surovy, Musrat Zahan" uniqKey="Surovy M" first="Musrat Zahan" last="Surovy">Musrat Zahan Surovy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706, Bangladesh.</nlm:affiliation><country xml:lang="fr">Bangladesh</country><wicri:regionArea>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706</wicri:regionArea><wicri:noRegion>Gazipur 1706</wicri:noRegion></affiliation></author><author><name sortKey="Islam, M Tofazzal" sort="Islam, M Tofazzal" uniqKey="Islam M" first="M Tofazzal" last="Islam">M Tofazzal Islam</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706, Bangladesh.</nlm:affiliation><country xml:lang="fr">Bangladesh</country><wicri:regionArea>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706</wicri:regionArea><wicri:noRegion>Gazipur 1706</wicri:noRegion></affiliation></author><author><name sortKey="Schuffler, Anja" sort="Schuffler, Anja" uniqKey="Schuffler A" first="Anja" last="Schüffler">Anja Schüffler</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Biotechnology and Drug Research , D-67663 Kaiserslautern, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Biotechnology and Drug Research , D-67663 Kaiserslautern</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Kaiserslautern</settlement></placeName></affiliation></author><author><name sortKey="Laatsch, Hartmut" sort="Laatsch, Hartmut" uniqKey="Laatsch H" first="Hartmut" last="Laatsch">Hartmut Laatsch</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26320597</idno><idno type="pmid">26320597</idno><idno type="doi">10.1021/acs.jafc.5b02366</idno><idno type="wicri:Area/Main/Corpus">000D75</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000D75</idno><idno type="wicri:Area/Main/Curation">000D75</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000D75</idno><idno type="wicri:Area/Main/Exploration">000D75</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae.</title><author><name sortKey="Mondol, Muhammad Abdul Mojid" sort="Mondol, Muhammad Abdul Mojid" uniqKey="Mondol M" first="Muhammad Abdul Mojid" last="Mondol">Muhammad Abdul Mojid Mondol</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Surovy, Musrat Zahan" sort="Surovy, Musrat Zahan" uniqKey="Surovy M" first="Musrat Zahan" last="Surovy">Musrat Zahan Surovy</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706, Bangladesh.</nlm:affiliation><country xml:lang="fr">Bangladesh</country><wicri:regionArea>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706</wicri:regionArea><wicri:noRegion>Gazipur 1706</wicri:noRegion></affiliation></author><author><name sortKey="Islam, M Tofazzal" sort="Islam, M Tofazzal" uniqKey="Islam M" first="M Tofazzal" last="Islam">M Tofazzal Islam</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706, Bangladesh.</nlm:affiliation><country xml:lang="fr">Bangladesh</country><wicri:regionArea>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706</wicri:regionArea><wicri:noRegion>Gazipur 1706</wicri:noRegion></affiliation></author><author><name sortKey="Schuffler, Anja" sort="Schuffler, Anja" uniqKey="Schuffler A" first="Anja" last="Schüffler">Anja Schüffler</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Biotechnology and Drug Research , D-67663 Kaiserslautern, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Biotechnology and Drug Research , D-67663 Kaiserslautern</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Kaiserslautern</settlement></placeName></affiliation></author><author><name sortKey="Laatsch, Hartmut" sort="Laatsch, Hartmut" uniqKey="Laatsch H" first="Hartmut" last="Laatsch">Hartmut Laatsch</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author></analytic><series><title level="j">Journal of agricultural and food chemistry</title><idno type="eISSN">1520-5118</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hypocreales (chemistry)</term><term>Molecular Structure (MeSH)</term><term>Phytophthora (cytology)</term><term>Phytophthora (drug effects)</term><term>Plant Extracts (chemistry)</term><term>Plant Extracts (isolation & purification)</term><term>Plant Extracts (pharmacology)</term><term>Spores (cytology)</term><term>Spores (drug effects)</term><term>Trichothecenes (chemistry)</term><term>Trichothecenes (isolation & purification)</term><term>Trichothecenes (pharmacology)</term><term>Vegetables (chemistry)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Extraits de plantes (composition chimique)</term><term>Extraits de plantes (isolement et purification)</term><term>Extraits de plantes (pharmacologie)</term><term>Hypocreales (composition chimique)</term><term>Légumes (composition chimique)</term><term>Phytophthora (cytologie)</term><term>Phytophthora (effets des médicaments et des substances chimiques)</term><term>Spores (cytologie)</term><term>Spores (effets des médicaments et des substances chimiques)</term><term>Structure moléculaire (MeSH)</term><term>Trichothécènes (composition chimique)</term><term>Trichothécènes (isolement et purification)</term><term>Trichothécènes (pharmacologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Plant Extracts</term><term>Trichothecenes</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Hypocreales</term><term>Vegetables</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Extraits de plantes</term><term>Hypocreales</term><term>Légumes</term><term>Trichothécènes</term></keywords><keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Phytophthora</term><term>Spores</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Phytophthora</term><term>Spores</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Phytophthora</term><term>Spores</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Phytophthora</term><term>Spores</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Plant Extracts</term><term>Trichothecenes</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Extraits de plantes</term><term>Trichothécènes</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Extraits de plantes</term><term>Trichothécènes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Plant Extracts</term><term>Trichothecenes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Molecular Structure</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Structure moléculaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The cytotoxicity of the extract obtained from Myrothecium roridum M10 and a characteristic (1)H signal at δH ∼8 led to the assumption that verrucarin/roridin-type compounds were present. Upscaling on rice medium led to the isolation of four new metabolites: verrucarins Y (1) and Z (6) (macrocyclic trichothecenes), bilain D (12) (a diketopiperazine derivative), and hamavellone C (14) (an unusual cyclopropyl diketone). In addition, nine known trichothecenes [verrucarin A (3), 16-hydroxyverrucarin A (5), verrucarin B (7), 16-hydroxyverrucarin B (8), verrucarin J (2), verrucarin X (4), roridin A (9), roridin L-2 (10), and trichoverritone (11)] and a bicyclic lactone [myrotheciumone A (15)] were identified. Their structures and configurations were determined by spectroscopic methods, published data, Mosher's method, and considering biosyntheses. Some trichothecenes showed motility inhibition followed by lysis of the zoospores against devastating Phytophthora nicotianae within 5 min. Compounds 2, 3, 7, and 9 also exhibited potent activities against Candida albicans and Mucor miehei. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26320597</PMID><DateCompleted><Year>2016</Year><Month>04</Month><Day>22</Day></DateCompleted><DateRevised><Year>2015</Year><Month>10</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1520-5118</ISSN><JournalIssue CitedMedium="Internet"><Volume>63</Volume><Issue>40</Issue><PubDate><Year>2015</Year><Month>Oct</Month><Day>14</Day></PubDate></JournalIssue><Title>Journal of agricultural and food chemistry</Title><ISOAbbreviation>J Agric Food Chem</ISOAbbreviation></Journal><ArticleTitle>Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae.</ArticleTitle><Pagination><MedlinePgn>8777-86</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1021/acs.jafc.5b02366</ELocationID><Abstract><AbstractText>The cytotoxicity of the extract obtained from Myrothecium roridum M10 and a characteristic (1)H signal at δH ∼8 led to the assumption that verrucarin/roridin-type compounds were present. Upscaling on rice medium led to the isolation of four new metabolites: verrucarins Y (1) and Z (6) (macrocyclic trichothecenes), bilain D (12) (a diketopiperazine derivative), and hamavellone C (14) (an unusual cyclopropyl diketone). In addition, nine known trichothecenes [verrucarin A (3), 16-hydroxyverrucarin A (5), verrucarin B (7), 16-hydroxyverrucarin B (8), verrucarin J (2), verrucarin X (4), roridin A (9), roridin L-2 (10), and trichoverritone (11)] and a bicyclic lactone [myrotheciumone A (15)] were identified. Their structures and configurations were determined by spectroscopic methods, published data, Mosher's method, and considering biosyntheses. Some trichothecenes showed motility inhibition followed by lysis of the zoospores against devastating Phytophthora nicotianae within 5 min. Compounds 2, 3, 7, and 9 also exhibited potent activities against Candida albicans and Mucor miehei. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mondol</LastName><ForeName>Muhammad Abdul Mojid</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Surovy</LastName><ForeName>Musrat Zahan</ForeName><Initials>MZ</Initials><AffiliationInfo><Affiliation>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Islam</LastName><ForeName>M Tofazzal</ForeName><Initials>MT</Initials><AffiliationInfo><Affiliation>Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University , Gazipur 1706, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schüffler</LastName><ForeName>Anja</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Biotechnology and Drug Research , D-67663 Kaiserslautern, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Laatsch</LastName><ForeName>Hartmut</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institute for Organic and Biomolecular Chemistry, Georg-August-University Göttingen , Tammannstrasse 2, D-37077 Göttingen, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>09</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Agric Food Chem</MedlineTA><NlmUniqueID>0374755</NlmUniqueID><ISSNLinking>0021-8561</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010936">Plant Extracts</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014255">Trichothecenes</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D006999" MajorTopicYN="N">Hypocreales</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015394" MajorTopicYN="N">Molecular Structure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010936" MajorTopicYN="N">Plant Extracts</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013170" MajorTopicYN="N">Spores</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014255" MajorTopicYN="N">Trichothecenes</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014675" MajorTopicYN="N">Vegetables</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Phytophthora</Keyword><Keyword MajorTopicYN="N">antibiotic activity</Keyword><Keyword MajorTopicYN="N">roridin</Keyword><Keyword MajorTopicYN="N">structure elucidation</Keyword><Keyword MajorTopicYN="N">verrucarin</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>9</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>9</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>4</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26320597</ArticleId><ArticleId IdType="doi">10.1021/acs.jafc.5b02366</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Bangladesh</li></country><region><li>Basse-Saxe</li><li>Rhénanie-Palatinat</li></region><settlement><li>Göttingen</li><li>Kaiserslautern</li></settlement></list><tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Mondol, Muhammad Abdul Mojid" sort="Mondol, Muhammad Abdul Mojid" uniqKey="Mondol M" first="Muhammad Abdul Mojid" last="Mondol">Muhammad Abdul Mojid Mondol</name></region><name sortKey="Laatsch, Hartmut" sort="Laatsch, Hartmut" uniqKey="Laatsch H" first="Hartmut" last="Laatsch">Hartmut Laatsch</name><name sortKey="Schuffler, Anja" sort="Schuffler, Anja" uniqKey="Schuffler A" first="Anja" last="Schüffler">Anja Schüffler</name></country><country name="Bangladesh"><noRegion><name sortKey="Surovy, Musrat Zahan" sort="Surovy, Musrat Zahan" uniqKey="Surovy M" first="Musrat Zahan" last="Surovy">Musrat Zahan Surovy</name></noRegion><name sortKey="Islam, M Tofazzal" sort="Islam, M Tofazzal" uniqKey="Islam M" first="M Tofazzal" last="Islam">M Tofazzal Islam</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E26 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E26 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PhytophthoraV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:26320597
|texte= Macrocyclic Trichothecenes from Myrothecium roridum Strain M10 with Motility Inhibitory and Zoosporicidal Activities against Phytophthora nicotianae.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26320597" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PhytophthoraV1
| This area was generated with Dilib version V0.6.38. |  |